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Test ID LBOR0174 PharmGx Panel

Useful For

Uses for Test:

  • To identify genotypes shown to have a drug-gene variant relationship.

AKA

Warfarin, Plavix, Codeine, Clopidogrel, CYP2C9, CYP2C19, CYP2D6, CYP4F2, IFNL3, CYP2C Cluster 

Specimen Type/Requirements

Lavender top (EDTA) tube - Whole Blood

 

Blood samples will not be accepted for patients that have undergone an allogenic transplant (e.g. bone marrow or peripheral stem cell) OR that have a history of chronic lymphocytic leukemia (CLL).

 

Transfusion patients:  Wait at least 2 weeks after a packed cell/platelet transfusion, and at least 4 weeks after a whole blood transfusion prior to blood draw for testing.

 

Chemotherapy patients:  DNA quality may be affected if patient has received chemotherapy within the last 120 days.  Clients will be contacted to provide additional specimen if DNA quality is insufficient.

 

All specimens should be sent in the original container and should not be aliquoted to another tube. In addition, the specimen submitted should ONLY be used for this testing and should not be shared with any other testing that would also utilize this specimen type.

 

Testing is not affected by hemolysis or lipemia.  

Specimen Volume

 Preferred Volume    2.0 - 4.0 mL  
 Minimum Volume    1.0 mL  

 

Stability/Transport

 Room Temperature    72 hours    
 Refrigerated    7 days    Preferred for transport  
 Frozen    Not Acceptable     

 

Performed Test Frequency

Monday through Friday

Report Available

5 - 7 days

Additional Information

The following 11 genes are included in this panel:

 

  • CYP2C9
  • VKORC1
  • SLCO1B1
  • TPMT
  • DPYD
  • CYP2C19
  • CYP3A5
  • CYP2D6
  • CYP4F2
  • IFNL3
  • CYP2C Cluster

 

See Pharmacogenomic Panel Testing for additional information. 

Methodology

Allele-specific PCR

Performing Lab

Sanford Medical Genetics Laboratory - Sioux Falls

CPT

81418