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Test ID NBLD0569 T-Cell Receptor Gene Rearrangement, PCR, Bone Marrow

Useful For

Determining whether a T-cell population is polyclonal or monoclonal

Specimen Type

Bone Marrow

Shipping Instructions

Specimen must arrive within 7 days (168 hours) of collection.

Necessary Information

Include relevant clinical information and cytogenetics results, if available.

Specimen Required


Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 2 mL

Collection Instructions:

1. Invert several times to mix bone marrow.

2. Send specimen in original tube. Do not aliquot.

Specimen Minimum Volume

1 mL

Reject Due To

Gross hemolysis Reject
Moderately to severely clotted Reject

Specimen Stability Information

Specimen Type Temperature Time Special Container
Bone Marrow Ambient (preferred) 7 days
  Refrigerated  7 days

Day(s) Performed

Monday through Friday

Report Available

5 to 10 days

Method Name

Polymerase Chain Reaction (PCR)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

81340-TCB (T cell antigen receptor, beta) (eg, leukemia and lymphoma), gene rearrangement analysis to detect abnormal clonal population(s); using amplification methodology (eg, PCR)

81342-TCG (T cell receptor, gamma) (eg, leukemia and lymphoma), gene rearrangement analysis, evaluation to detect abnormal clonal population(s)

81479 (if appropriate for government payers)

Reporting Name

T Cell Receptor Gene Rearrange, BM

Reference Values

An interpretive report will be provided.

Positive, negative, or indeterminate for a clonal T-cell population

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.


1. Hematopathology Patient Information (T676) in Special Instructions

2. If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request (T726) with the specimen.

Secondary ID

Sanford Laboratories - Fargo Additional Information:


Result Code Result Code Description
21719 Final Diagnosis