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Test ID NBLD0553 Amphetamines Confirmation, Random, Urine

Important Note

Effective 2-11-2025:  Due to instrumentation issues, test results will be extended 3 to 5 days beyond currently published turnaround times.  The duration of this delay is anticipated to be approximately 2 to 4 weeks.  An update will be provided when normal testing patterns resume. 

Useful For

Confirming drug exposure involving amphetamines such as amphetamine and methamphetamine, phentermine, pseudoephedrine/ephedrine, methylenedioxyamphetamine (MDA), and methylenedioxymethamphetamine (MDMA)

Specimen Type

Urine


Ordering Guidance


For situations where chain of custody is required, a Chain of Custody Kit (T282) is available. For chain-of-custody testing, order AMPHX / Amphetamines Confirmation, Chain of Custody, Random, Urine.

 

Additional drug panels and specific requests are available; call 800-533-1710.



Additional Testing Requirements


If urine creatinine is required or adulteration of the specimen is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Urine.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting less than 1 mL will compromise our ability to perform all necessary testing.


Specimen Minimum Volume

1.5 mL

Reject Due To

Gross hemolysis OK
Gross icterus OK

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Day(s) Performed

Monday through Friday

Report Available

3 to 5 days

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

G0480

80325 (if appropriate for select payers(

80359 (if appropriate for select payers)

Clinical Toxicology CPT Code Client Guidance

Reporting Name

Amphetamines Confirmation, U

Reference Values

Negative

Positive results are reported with a quantitative result.

 

Cutoff concentrations by liquid chromatography tandem mass spectrometry:

Amphetamine: 25 ng/mL

Methamphetamine: 25 ng/mL

Phentermine: 25 ng/mL

Methylenedioxyamphetamine: 25 ng/mL

Methylenedioxymethamphetamine: 25 ng/mL

Pseudoephedrine/ephedrine: 25 ng/mL reported as negative

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Secondary ID

8257

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.

Sanford Laboratories - Fargo Additional Information:

SANFORD INTERFACE BUILD INFORMATION

Result Code Result Code Description
17368 Amphetamine-By GC/MS
17369 Phentermine-By GC/MS
17370 Methamphetamine-By GC/MS
17371 Pseudoephedrine/Ephedrine-By GC/MS
17372 MDA (Ecstasy Metabolite)-By GC/MS
17373 MDMA  (Ecstasy)- By GC/MS
17374 Interpretation
17375 Chain of Custody