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Test ID NBLD0424 Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Spinal Fluid

Useful For

Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)

 

Diagnosis of autoimmune AQP4 channelopathy

 

Distinguishing NMOSD from multiple sclerosis early in the course of disease

Specimen Type

CSF


Advisory Information


 



Necessary Information


Include relevant clinical information, name, phone number, mailing address, and e-mail address (if applicable) of ordering physician.



Specimen Required


Collection Container/Tube: Sterile vial

Specimen Volume: 3 mL


Specimen Minimum Volume

2 mL

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

NA

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Day(s) and Time(s) Performed

Monday, Tuesday, Thursday; 6 p.m.

Analytic Time

5 days

Method Name

Flow Cytometry

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86255

86256-NMO/AQP4-IgG FACS titer (if appropriate)

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
NMOTC NMO/AQP4 FACS Titer, CSF No No

Testing Algorithm

When the results of this assay require further evaluation, NMOTC / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay Titer, Spinal Fluid will be performed at an additional charge.

Reporting Name

NMO/AQP4 FACS, CSF

Reference Values

Negative

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Secondary ID

38325
Sanford Laboratories - Fargo Additional Information:

SANFORD INTERFACE BUILD INFORMATION

Result Code Result Code Description
16493 NMO/AQP4-IgG, CSF