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HelpTest ID NBLD0045 Alpha-Fetoprotein, Amniotic Fluid
Useful For
Screening for open neural tube defects or other fetal abnormalities
Follow-up testing for patients with elevated serum alpha-fetoprotein results or in conjunction with cytogenetic testing
Specimen Type
Amniotic FldNecessary Information
The following information is required:
1. Estimated due date by ultrasound
2. Collection date
3. Gestational age must be between 13 and 24 weeks; 16 to 18 weeks preferred.
If not ordering electronically, provide information on Second Trimester Maternal Screening Alpha-Fetoprotein / Quad Screen Patient Information (T595) and send with specimen.
Specimen Required
Container/Tube: Amniotic fluid container
Specimen Volume: 0.75 mL
Collection Instructions: Do not centrifuge.
Specimen Minimum Volume
0.5 mL
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Amniotic Fld | Refrigerated (preferred) | 7 days | |
| Ambient | 7 days |
Day(s) Performed
Monday through Friday
Report Available
2 to 19 daysMethod Name
AFPA: Immunoenzymatic Assay
ACHE_: Polyacrylamide Electrophoresis
Reporting Name
Alpha Fetoprotein, AFPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
82106
82013 (if appropriate)
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| ACHE_ | Acetylcholinesterase, AF | Yes | No |
Testing Algorithm
If alpha-fetoprotein is positive, then acetylcholinesterase will be performed at an additional charge.
Special Instructions
Reference Values
< 2.0 multiples of median (MoM)
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Forms
Second Trimester Maternal Screening Alpha-Fetoprotein / Quad Screen Patient Information (T595) is required.
Secondary ID
9950SANFORD INTERFACE BUILD INFORMATION
| Result Code | Result Code Description |
|---|---|
| 17986 | Collection Date |
| 17987 | EDD by US Scan |
| 17988 | Last Menstrual Period (LMP) |
| 17989 | EDD by LMP |
| 17990 | GA at Collection by Scan |
| 17991 | GA at Collcetion by Dates |
| 17992 | GA Used |
| 17993 | Alpha Fetoprotein, AF |
| 17994 | Results |
| 17995 | Interpretation |
| 17996 | Additional Comments |
| 17997 | Follow Up |
| 17998 | General Tests Info |