Important Note
Effective 5/15/2026:
Quest has resumed testing for its AD-Detect® Beta-Amyloid 42/40 Ratio, Plasma and AD-Detect® ABeta 42/40 and p-tau217 Evaluation, Plasma tests after we temporarily suspended testing due to a technical issue, which has since been resolved. We are performing testing on a first in, first out basis. While we are increasing our testing capacity, please expect an additional 10-16 days beyond our standard turnaround time for AD-Detect® Beta-Amyloid 42/40 Ratio, Plasma and AD-Detect® ABeta 42/40 and p-tau217 Evaluation, Plasma testing. All samples are stored at optimal temperatures to preserve stability. We will provide status updates every Friday until normal operations resume.
Target Resolution Date: 6/24/2026
Effective 5/1/2026:
The p-tau 217 portion of the profile TC 14258-D-Detect™ Abeta 42/40 and p-tau217 evaluation: Reagents have been received and testing has resumed. Please add 8-10 days to TAT. Update will be provided 5/6/26. Target Resolution Date: 5-11-26
Effective 4/28/2026:
Technical issues for ABeta 42/40 have been resolved, and processing has resumed on a first in, first out basis. To clear the backlog, we are increasing our testing capacity. Please expect an additional 10-16 days beyond our standard turnaround time. All samples are currently stored at optimal temperatures. We will provide status updates every Friday until normal operations resume.
Target Resolution Date: 6-9-2026
The p-tau 217 portion of the profile TC 14258-D-Detect™ Abeta 42/40 and p-tau217 evaluation: We are unable to perform the assay due to a reagent backorder from our vendor. Samples will be held at optimal temperature. Updates will be provided as soon as they are available.
Effective 4/15/2026: Technical issues for ABeta 42/40 have been resolved, and testing has resumed on a first in, first out basis. Please expect extended delays. An update will be provided on 4/24/26.
The p-tau 217 portion of the profile TC 14258-D-Detect™ Abeta 42/40 and p-tau217 evaluation will still be performed. If you desire result, please contact Client Services.
Effective 4/3/2026: Due to reagent backorder and technical issues, testing will be temporarily unavailable. Samples are being held at optimal stability. Update to be provided when reagents are received and issue is resolved. Target Resolution Date: 4-24-2026.
Specimen Type/Requirements
K2 Lavender top (EDTA) tube - Plasma
Collect blood into a K2 EDTA (lavender-top tube) and mix by inversion 10 times. Centrifuge to separate plasma from cells within 1 hour of collection. Carefully transfer plasma into 2 separate polypropylene aliquot tubes. Do not transfer to conical tubes. Store and ship frozen.
Test is affected by hemolysis.
Patients should be cautioned to stop biotin consumption at least 72 hours prior to collection of a sample.
Quest Diagnostics does not perform this test for individuals under the age of 18.