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Test ID BLOD1452 Thyroglobulin, Tumor Marker Reflex, Serum

Useful For

Reporting of accurate thyroglobulin results, depending on the antithyroglobulin antibodies status of the patient

 

Accurate measurement of serum thyroglobulin in patients with known or suspected antithyroglobulin autoantibodies or possible heterophile antibodies

Specimen Type

Serum Red


Specimen Required


Patient Preparation: For 12 hours before specimen collection, patient should not take multivitamins or dietary supplements (eg, hair, skin, and nail supplements) containing biotin (vitamin B7).

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: None (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

1.25 mL

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  72 hours

Day(s) Performed

Monday through Saturday

Report Available

1 to 6 days

Method Name

HTGT: Immunoenzymatic Assay

TGMS: Tryptic Protein Fragmentation, purified with Immunocapture, Analysis by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) (This service is performed pursuant to an agreement with SISCAPA Assay Technologies Inc. covering US Patent 7,632,686)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86800

84432 (if appropriate)

Testing Algorithm

This test begins with the analysis of thyroglobulin antibody by immunoassay. If the thyroglobulin antibody result is negative (<1.8 IU/mL), then thyroglobulin testing will be performed by immunoassay.

 

If the thyroglobulin antibody result is positive (≥1.8 IU/mL), then thyroglobulin testing will be performed by mass spectrometry.

Reporting Name

Thyroglobulin Reflex to MS or IA

Reference Values

THYROGLOBULIN ANTIBODY

<1.8 IU/mL

 

THYROGLOBULIN, TUMOR MARKER

≤33 ng/mL

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HTGT Thyroglobulin, Tumor Marker, IA, S No No
TGMS Thyroglobulin, Mass Spec., S Yes No

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.

Secondary ID

62936
Sanford Laboratories - Fargo Additional Information:

SANFORD INTERFACE BUILD INFORMATION

Result Code Result Code Description
19794 Thyroglobulin Antibody, S