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Test ID BLOD0207 Sex Hormone-Binding Globulin, Serum

Useful For

Diagnosis and follow-up of women with signs or symptoms of androgen excess (eg, polycystic ovarian syndrome and idiopathic hirsutism)

 

An adjunct in monitoring sex-steroid and antiandrogen therapy

 

An adjunct in the diagnosis of disorders of puberty

 

An adjunct in the diagnosis and follow-up of anorexia nervosa

 

An adjunct in the diagnosis of thyrotoxicosis (tissue marker of thyroid hormone excess)

 

A possible adjunct in diagnosis and follow-up of insulin resistance and cardiovascular and type 2 diabetes risk assessment, particularly in women

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Method Name

Immunoenzymatic Assay

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84270

Secondary ID

608102

Reporting Name

Sex Hormone-Binding Globulin, S

Reference Values

CHILDREN:

Males

 

Tanner Stages

Mean Age

Reference Interval (nmol/L)

Stage I

10.4

17-135

Stage II

11.1

21-114

Stage III

12.7

12-138

Stage IV

14.5

7.7-67

Stage V

14.2

3.9-40

Females

Tanner Stages

Mean Age

Reference Interval (nmol/L)

Stage I

10.5

16-182

Stage II

10.9

24-121

Stage III

12.5

18-87

Stage IV

14

7.7-108

Stage V

14.9

10-79

 

ADULTS:

Males

≥18 years: 13.3-89.5 nmol/L

Females

18-46 years: 18.2-135.5 nmol/L

47-91 years: post-menopausal: 16.8-125.2 nmol/L

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.