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HelpTest ID BLOD5035 Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum
Useful For
Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines
Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines
Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies
Specimen Type
SerumOrdering Guidance
This test is the preferred test for patients previously tested for Streptococcus pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment).
The preferred test for patients being evaluated for possible immunodeficiency or for assessment of pneumococcal vaccination response (initial evaluation) is PNTOR / Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum
The preferred test for patients previously tested for total Streptococcus pneumoniae antibodies (as part of follow up testing or part of pre/post vaccine assessment) is PNTO / Streptococcus pneumoniae IgG Antibodies, Total, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL Serum
Collection Instructions: Centrifuge and aliquot serum into plastic vial
Specimen Minimum Volume
Serum: 0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Day(s) Performed
Monday through Friday
Report Available
4 to 6 daysMethod Name
Bead-Based Multiplex Immunoassay
Reporting Name
S. pneumoniae IgG Ab,23 serotypes,SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Secondary ID
619921CPT Code Information
86581
Reference Values
Results are reported in mcg/mL
|
Serotype |
Normal value |
|
1 (1) |
≥1.0 |
|
2 (2) |
≥1.0 |
|
3 (3) |
≥1.0 |
|
4 (4) |
≥1.0 |
|
5 (5) |
≥1.0 |
|
8 (8) |
≥1.0 |
|
9N (9) |
≥1.0 |
|
12F (12) |
≥1.0 |
|
14 (14) |
≥1.0 |
|
17F (17) |
≥1.0 |
|
19F (19) |
≥1.0 |
|
20 (20) |
≥1.0 |
|
22F (22) |
≥1.0 |
|
23F (23) |
≥1.0 |
|
6B (26) |
≥1.0 |
|
10A (34) |
≥1.0 |
|
11A (43) |
≥1.0 |
|
7F (51) |
≥1.0 |
|
15B (54) |
≥1.0 |
|
18C (56) |
≥1.0 |
|
19A (57) |
≥1.0 |
|
9V (68) |
≥1.0 |
|
33F (70) |
≥1.0 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Forms
If not ordering electronically, complete, print, and send a General Test Request (T239) with the specimen.