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Test ID BLOD1806 Karius Spectrum, Direct Ship, Plasma

Important Note

Testing is intended for hospital inpatients.  See Testing Algorithms at the bottom of the page for considerations of when to use the Karius Spectrum Test.

Follow collection instructions below.

Specimens must be sent to your local Sanford Laboratories Sendout Department to be shipped to Karius directly. 

Useful For

Rapid and minimally invasive detection of deep-seated and difficult-to-diagnose systemic infections throughout the body

 

Provide antimicrobial resistance detection for microbes known to utilize the antimicrobial resistance mechanism

Specimen Type

Plasma


Ordering Guidance


Order this test when shipping specimens directly to Karius.



Shipping Instructions


1. Place the specimen in the biohazard bag with an absorbent pad.

2. Wrap the ambient gel pack around the specimen bag.

3. Place the wrapped specimen bag in the foil bubble mailer and then in the test kit cardboard box.

4. Include the batch sheet from MayoACCESS or MayoLINK in the test kit cardboard box.

5. Ship ambient to Karius Labs. If the ambient specimen will not arrive at Karius Labs within 4 days, order KPLA / Karius Spectrum, Plasma and ship specimen frozen to Mayo Clinic Laboratories.



Specimen Required


Supplies: Karius KDPLA Kit (T1014)

Collection Container/Tube:

Preferred: Plasma Preparation Tube (PPT)

Acceptable: Lavender top (K2 EDTA)

Submission Container/Tube:

Preferred: PPT

Acceptable: Sterile polypropylene tube

Specimen Volume: 1 mL Plasma

Collection Instructions:

1. Gently invert tube 8 to 10 times to mix whole blood.

2. Centrifuge specimen as follows:

 a. For PPT: Within 6 hours of collection, centrifuge at 1100 x g for 10 minutes.

 b. For K2 EDTA:

  i. Within 24 hours of collection, centrifuge at 1600 x g for 10 minutes. For tubes less than 4 mL, refer to tube manufacturer's instructions for centrifugation speed and time.

  ii. Aliquot 1 mL of plasma into a sterile polypropylene tube, taking care not to disturb the buffy coat.

3. See Shipping Instructions for how to package and ship the specimen to Karius Labs.


Specimen Minimum Volume

Plasma: 0.7 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Ambient (preferred) 4 days
  Frozen  180 days

Reject Due To

Incomplete or improper plasma separation Reject

Day(s) Performed

Monday through Saturday

Report Available

2 to 6 days

Method Name

Metagenomic Sequencing

Reporting Name

Karius Spectrum Direct, P

Performing Laboratory

KARIUS LABORATORY DIRECT SHIP

Secondary ID

623289

CPT Code Information

0152U

Reference Values

An interpretive report will be provided.

Test Classification

The Karius Spectrum test was developed and its performance characteristics determined by Karius. The Karius laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA '88) and is accredited by the College of American Pathologists (CAP) to perform high-complexity clinical laboratory testing. This test has not been reviewed or cleared by the US Food and Drug Administration.