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Test ID BLOD0406 Lamotrigine, Serum

Useful For

Monitoring serum concentration of lamotrigine

 

Assessing compliance

 

Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Collect blood immediately before next scheduled dose.

2. For sustained-release formulations only, collect blood a minimum of 12 hours after last dose.

3. Centrifuge within 2 hours of collection

4. For red-top tubes, immediately aliquot serum into a plastic vial.

5. For serum gel tubes, aliquot serum into a plastic vial within 24 hours of collection.


Specimen Minimum Volume

0.5 mL

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
 

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80175

Reporting Name

Lamotrigine, S

Reference Values

Patients receiving therapeutic doses usually have lamotrigine concentrations of 3.0-15.0 mcg/mL.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-General Request (T239)

-Therapeutics Test Request (T831)

Secondary ID

80999
Sanford Laboratories - Fargo Additional Information:

SANFORD INTERFACE BUILD INFORMATION

Result Code Result Code Description
53 Lamotrigine