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Test ID BLOD0127 Insulin Antibodies, Serum

Reporting Name

Insulin Abs, S

Useful For

Predicting the future development of type 1 diabetes in asymptomatic children, adolescents, and young adults, when used in conjunction with family history, HLA-typing, and other autoantibodies, including GD65S/81596 Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Serum and islet cell antigen 2 (IA-2) antibodies


Differential diagnosis of type 1 versus type 2 diabetes


Evaluating diabetics with insulin resistance in patients with established diabetes (type 1 or type 2)


Investigation of hypoglycemia in nondiabetic subjects

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type


Specimen Required


Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1.5 mL

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

≤0.02 nmol/L

Reference values apply to all ages.

Day(s) and Time(s) Performed

Sunday, Wednesday; 10 p.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
INAB Insulin Abs, S 60463-7


Result ID Test Result Name Result LOINC Value
8666 Insulin Abs, S 60463-7

Analytic Time

3 days/negative 5 days/positive

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross reject



Method Name

Radioimmunoassay (RIA)